Evidence-Based Health · applied critical appraisal Português

Method glossary

surrogate outcome

Intermediate marker (e.g. GFR, cholesterol), not the event that matters to the patient.

Source
GRADE Handbook
GRADE Working Group
https://gdt.gradepro.org/app/handbook/handbook.html
Where, in the source
§3.4 — Surrogate (substitute) outcomes
Checked at the source on
2026-06-13
Verbatim
The official passage from this source is transcribed and checked in our own method document, with the date of verification.
Who wrote this
The wording of this entry is ours, written for people outside the field. The concept and its limits come from the source above, against which this wording is checked — it is neither a translation nor a copy of it.

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